Unfortunately sometimes such spreadsheets have to stay up to date and people keep modifying them. And when it comes to using formulas, maintaining a spreadsheet is a must (CSV preserves only final values).
I had such a situation in one of my past projects, clients uploaded XLS files via a web form and a python script had to decode appropriate evaluated cells and load them to the database. There are many platform dependent (windows) packages for this purpose requiring some M$ Office DLLs present, but since I didn't want to deploy this application on windows I started looking for a cross-platform solution. I decided to used xlrd, a cross-platform tool compatible with python 2.7. You can get it using pip:
~ $ sudo pip install xlrd
Now for an example:
import xlrd #open the spreadsheet workbook = xlrd.open_workbook("test.xls") #select the first sheet sheet = workbook.sheet_by_index(0) #get data from column C (2), row 10 (9) #non-negative numeration data = sheet.cell(colx=2,rowx=9).value print "Cell C,10: %s" % data
It's quite easy, however its best to implement some mapping function, so you don't have to evaluate the column number for every letter (cell AXC, 19221 could be quite tricky ;-))
~KR